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Erythromycin's elimination half-life ranges between 1.5 and 2.0 hours and is between 5 and 6 hours in patients with end-stage renal disease. Erythromycin levels peak in the serum 4 hours after dosing; ethylsuccinate peaks 0.5–2.5 hours after dosing, but can be delayed if digested with food. [39]
Use of 1% tetracycline ointment, 0.5% erythromycin ointment, or 1-2% silver nitrate solution (Credé's method) into the eyes of babies immediately after birth. [ 6 ] Single injection of ceftriaxone IM or IV should be given to infants born to mothers with untreated gonococcal infection.
Credé prophylaxis is the practice of washing a newborn's eyes with a 2% silver nitrate solution to protect against neonatal conjunctivitis caused by Neisseria gonorrhoeae, thereby preventing blindness.
Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]
A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
Bacitracin/polymyxin B (trade name Polysporin among others) is a topical antibiotic cream or ointment. [1] The active ingredients are polymyxin B, bacitracin and occasionally garamycin or gramicidin.
Ophthalmia (/ ɒ p ˈ θ æ l m i ə /; also called ophthalmitis, and archaically obtalmy) [1] is inflammation of the eye. It results in congestion of the eyeball, often eye-watering, redness and swelling, itching and burning, and a general feeling of irritation under the eyelids. Ophthalmia can have different causes, such as infection from ...
ATC code S01 Ophthalmologicals is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.