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  2. Systemic inflammatory response syndrome - Wikipedia

    en.wikipedia.org/wiki/Systemic_inflammatory...

    SIRS is a serious condition related to systemic inflammation, organ dysfunction, and organ failure. It is a subset of cytokine storm, in which there is abnormal regulation of various cytokines. [6] SIRS is also closely related to sepsis, in which patients satisfy criteria for SIRS and have a suspected or proven infection. [2] [3] [4] [7]

  3. Sepsis - Wikipedia

    en.wikipedia.org/wiki/Sepsis

    However, the American College of Chest Physicians (CHEST) raised concerns that qSOFA and SOFA criteria may lead to delayed diagnosis of serious infection, leading to delayed treatment. [49] Although SIRS criteria can be too sensitive and not specific enough in identifying sepsis, SOFA also has its limitations and is not intended to replace the ...

  4. Hypertension - Wikipedia

    en.wikipedia.org/wiki/Hypertension

    [9] [10] Of all people with hypertension, about 46% do not have a diagnosis of hypertension and are unaware that they have the condition. [13] [9] In 1975, almost 600 million people had a diagnosis of hypertension, a number which increased to 1.13 billion by 2015 mostly due to risk factors for hypertension increasing in low- and middle-income ...

  5. Management of hypertension - Wikipedia

    en.wikipedia.org/wiki/Management_of_hypertension

    Guidelines for treating resistant hypertension have been published in the UK [45] and US. [46] It has been proposed that a proportion of resistant hypertension may be the result of chronic high activity of the autonomic nervous system, known as "neurogenic hypertension". [47] Low adherence to treatment is an important cause of resistant ...

  6. Abdominal compartment syndrome - Wikipedia

    en.wikipedia.org/wiki/Abdominal_compartment_syndrome

    The gut is the most sensitive to intra-abdominal hypertension, and it develops evidence of end-organ damage before alterations are observed in other systems. [13] In a recent systematic review, Holodinsky et al. described 25 risk factors associated with IAH (intra-abdominal hypertension) and 16 with ACS (abdominal compartment syndrome).

  7. Multiple organ dysfunction syndrome - Wikipedia

    en.wikipedia.org/wiki/Multiple_organ_dysfunction...

    Both SIRS and sepsis could ultimately progress to multiple organ dysfunction syndrome. In one-third of the patients, however, no primary focus can be found. [1] Multiple organ dysfunction syndrome is well established as the final stage of a continuum: SIRS + infection → sepsis → severe sepsis → Multiple organ dysfunction syndrome.

  8. Hypertensive emergency - Wikipedia

    en.wikipedia.org/wiki/Hypertensive_emergency

    Kidney biopsy showing thrombotic microangiopathy, a histomorphologic finding seen in malignant hypertension. The pathophysiology of hypertensive emergency is not well understood. Failure of normal autoregulation and an abrupt rise in systemic vascular resistance are typical initial components of the disease process. [6]

  9. Comparison of international blood pressure guidelines

    en.wikipedia.org/wiki/Comparison_of...

    Guidelines on the choice of agents and how best to step up treatment for various subgroups in hypertension (high blood pressure) have changed over time and differ between countries. A Comparison of International Guidelines on Goal Blood Pressure and Initial Therapy for Adults With Hypertension (adapted from JNC 8 guidelines [ 1 ] )