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Adults need about 2.4 micrograms of B12 a day (that much can be found in one portion of salmon, canned tuna or ground beef), with pregnant and nursing women needing slightly more (2.6 and 2.8 mcg ...
In the same study, over 60% of pregnant women were deficient in vitamin B 12, which was considered to increase the risk of gestational and later diabetes in the mothers. [41] Increased longitudinal cohort studies or randomised controlled trials are required to understand the mechanisms between vitamin B 12 and metabolic outcomes, and to ...
This may be due to a dietary deficiency, malabsorption in the terminal ileum, lack of intrinsic factor secreted from gastric parietal cells, or low gastric pH inhibiting attachment of intrinsic factor to ileal receptors. [10] The disease can also be caused by inhalation of nitrous oxide, which inactivates vitamin B12. [11]
Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the US. Among those over the age of 60, about 2% have the condition. [8] It more commonly affects people of northern European descent. [2] Women are more commonly affected than men. [15] With proper treatment, most people live normal lives. [5]
Pernicious anaemia is a lifelong condition that affects nearly 5 in 100,000 people in the UK.
Vitamin b12 deficiency can cause mood swings and tiredness. And no, you don't need to be a vegan to deal with this problem.
Niacin deficiency is a consequence of a diet low in both niacin and the amino acid tryptophan, a precursor for the vitamin. Low plasma tryptophan is a non-specific indicator, meaning it can have other causes. The signs and symptoms of niacin deficiency start to revert within days of oral supplementation with large amounts of the vitamin. [23] [24]
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.