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  2. Antiarthritics - Wikipedia

    en.wikipedia.org/wiki/Antiarthritics

    The adverse reactions of biologic response modifier therapies are associated with their mechanism of action that disrupts the immune homeostasis of the human body. [15] These inhibitory biologics cause suppression of the immune response resulting in an increase in risk and susceptibility to infection. [14] [15] Common infections include: [14] Colds

  3. Biological response modifier - Wikipedia

    en.wikipedia.org/wiki/Biological_response_modifier

    For people with moderate to severe psoriatic arthritis, biologics can provide some relief of the symptoms, [4] and even slow down or halt the progression of the disease. Classes of biologics typically used for psoriatic arthritis include TNF inhibitors, anti-IL17-A antibodies, IL-23 antibodies, and those that act on both IL-12 and IL-23. [7]

  4. Disease-modifying antirheumatic drug - Wikipedia

    en.wikipedia.org/wiki/Disease-modifying_anti...

    DMARDs help control arthritis, but do not cure the disease. For that reason, if remission or optimal control is achieved with a DMARD, it is often continued as a maintenance dosage. Discontinuing a DMARD may reactivate disease or cause a "rebound flare", with no assurance that disease control will be re-established upon resumption of the ...

  5. Adalimumab - Wikipedia

    en.wikipedia.org/wiki/Adalimumab

    Adalimumab, sold under the brand name Humira and others, is a disease-modifying antirheumatic drug and monoclonal antibody used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and uveitis.

  6. Cytokine release syndrome - Wikipedia

    en.wikipedia.org/wiki/Cytokine_release_syndrome

    Moreover, while tocilizumab (anti-IL-6R monoclonal antibody) may have an anti-inflammatory and antipyretic effect, it has been shown to increase serum levels of IL-6 by saturating the receptor, thus driving the cytokine across the blood brain barrier (BBB) and worsening neurotoxicity. [26]

  7. FDA Issues Urgent Warning on Dangers of Common Dog Medication

    www.aol.com/lifestyle/fda-issues-urgent-warning...

    The United States Food and Drugs Administration is warning pet owners about a common medication given to pets to treat arthritis. The F.D.A. now says that the drug Librela may be associated with ...