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Photodynamic therapy is also used to relieve symptoms of some cancers, including esophageal cancer when it blocks the throat and non-small cell lung cancer when it blocks the airways. [ 26 ] When cells that have absorbed photosensitizers are exposed to a specific wavelength of light, the photosensitizer produces a form of oxygen, called an ...
Porfimer sodium, sold as Photofrin, is a photosensitizer used in photodynamic therapy and radiation therapy and for palliative treatment of obstructing endobronchial non-small cell lung carcinoma and obstructing esophageal cancer. Porfimer is a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units. [1]
Photodynamic therapy (PDT) is a ternary treatment for cancer involving a photosensitizer, tissue oxygen, and light (often using lasers [13]). PDT can be used as treatment for basal cell carcinoma (BCC) or lung cancer; PDT can also be useful in removing traces of malignant tissue after surgical removal of large tumors. [14]
Talaporfin (INN, also known as aspartyl chlorin, mono-L-aspartyl chlorin e6, NPe6, or LS11) is a chlorin based photosensitizer used in photodynamic therapy (PDT). It absorbs red light at 664-667 nm normally provided by a laser tuned to this wavelength. [1] It was approved in Japan (in 2004) for PDT of lung cancer and marketed as Laserphyrin. [2]
Photoimmunotherapy (PIT) is an oncological treatment that combines photodynamic therapy of tumor with immunotherapy treatment. Combining photodynamic therapy with immunotherapy enhances the immunostimulating response and has synergistic effects for metastatic cancer treatment. [1] [2] [3] PIT is type of molecular targeted cancer therapy, which ...
While blue light therapy has similar mechanisms for skin enhancement as red light therapy, its usage for photodynamic therapies in treating cancer are slightly different. Blue light therapy stimulates immune system defences, destroys blood vessels that help cancer cells grow, and causes cell death by reacting with oxygen. [16]
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