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Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas.
Symptoms of Prediabetes. Prediabetes doesn’t come with many symptoms, so most people with the conadition — about 90 percent — don’t know they have it.. If you do experience prediabetes ...
Prediabetes is a component of metabolic syndrome and is characterized by elevated blood sugar levels that fall below the threshold to diagnose diabetes mellitus.It usually does not cause symptoms but people with prediabetes often have obesity (especially abdominal or visceral obesity), dyslipidemia with high triglycerides and/or low HDL cholesterol, and hypertension. [1]
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis . Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair.
Prediabetes, often considered the step before diabetes, is when you have higher than usual blood glucose (blood sugar) levels. Your levels aren’t high enough to be classified as type 2 diabetes.
Opioid treatment for chronic low back pain increases the risk for lifetime illicit drug use [100] and the effect of long-term use of opioids for lower back pain is unknown. [101] For older people with chronic pain, opioids may be used in those for whom NSAIDs present too great a risk, including those with diabetes, stomach or heart problems.
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