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The effects of rosuvastatin on low-density lipoprotein (LDL) cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.
JUPITER was a randomized double-blind placebo-controlled study investigating the use of rosuvastatin in the primary prevention of cardiovascular disease.The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP).
AstraZeneca (AZN) scored a win on Tuesday, when a Food and Drug Administration advisory panel recommended broader use of Crestor, the company's cholesterol-lowering drug. The panel recommended ...
Randomized controlled trials have found these foodstuffs to reduce circulating cholesterol, but the quality of the trials has been judged to be low. [177] Due to patent expiration, most of the block-buster branded statins have been generic since 2012, including atorvastatin, the largest-selling [ 178 ] branded drug.
It’s these bioactive compounds and antioxidants that are the keys to lentils ability to help reduce blood pressure, LDL cholesterol, and the risk of chronic cardiovascular disease. Just one cup ...
That’s why some people are able to lower their cholesterol naturally with diet and other changes, and others need to take medication, such as statins, as well, Dr. Victor says.
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