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Sterne was the first to try metformin on humans for the treatment of diabetes; he coined the name "Glucophage" (glucose eater) for the medication and published his results in 1957. [ 161 ] [ 168 ] Metformin became available in the British National Formulary in 1958.
SGLT2 inhibitors are used in the treatment of type 2 diabetes. Apart from blood sugar control, gliflozins have been shown to provide significant cardiovascular benefit in people with type 2 diabetes. [2] [3] As of 2014, several medications of this class had been approved or were under development. [4]
Sitagliptin, sold under the brand name Januvia among others, is an anti-diabetic medication used to treat type 2 diabetes. [8] It is in the dipeptidyl peptidase-4 (DPP-4) inhibitor class and works by increasing the production of insulin and decreasing the production of glucagon by the pancreas. [8]
Semaglutide, the active ingredient in diabetes drugs that have also become popular as a weight-loss aid, is primarily available in injectable form. This includes the two most widely used drugs ...
DPP-4 inhibitors are another class of anti-diabetes drugs with a different mechanism. These oral medications work by increasing levels of glucagon-like peptide-1 (GLP-1), which increases insulin ...
SGLT-2 inhibitors are a class of medications that treat type 2 diabetes. The medications help keep the kidneys from reabsorbing too much glucose and allow you to pee it out instead of circulating ...
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