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Pepto-Bismol is an over-the-counter drug currently produced by the Procter & Gamble company in the United States, Canada and the United Kingdom. Pepto-Bismol is made in chewable tablets [ 24 ] and swallowable caplets, [ 25 ] but it is best known for its original formula, which is a thick liquid.
The active ingredient in Kaopectate has changed since its original creation. Originally, kaolinite was used as the adsorbent and pectin as the emollient. Attapulgite (a type of absorbent clay) replaced the kaolinite in the 1980s, but was banned by the U.S. Food and Drug Administration in a ruling made in April 2003.
The company’s mixture called Cholera Infantum, later renamed Pepto-Bismol, appeared for the first time in 1901. Its principal use was for infants with severe diarrhea. In 1907, Acetylsalicylic acid tablets were added to the company’s product line.
Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), bismuth subsalicylate (Pepto-Bismol), [1] diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine.
Canada, UK Withdrawn from US in 2005 due to hepatotoxicity. [41] [3] Pentobarbital: 1980 Norway Risk of fatal overdose. [3] Pentylenetetrazol: 1982 US Withdrawn for inability to produce effective convulsive therapy, and for causing seizures. Pergolide (Permax) 2007 US Risk for heart valve damage. [2] Perhexiline: 1985 UK, Spain Neurologic and ...
Pepto-Bismol over-the-counter drug for minor digestive system upset (acquired as part of Norwich Eaton Pharmaceuticals in 1982) Prilosec OTC (licensed from AstraZeneca) Rolaids (acquired in 2024 from Lil' Drug Store Products) Sangobion (acquired from Merck Group) Scope mouthwash; Seven Seas (acquired from Merck Group) Vicks cough and cold products
A category for drugs withdrawn from the market after marketing commenced for any reason (voluntarily or involuntarily). For drug candidates that were abandoned prior to being marketed due to side effects, lack of efficacy, superior competitors, or other reasons, see Category:Abandoned drugs
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