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Spermatogenesis is the process by which haploid spermatozoa develop from germ cells in the seminiferous tubules of the testicle. This process starts with the mitotic division of the stem cells located close to the basement membrane of the tubules. [ 1 ]
Spermiogenesis is the final stage of spermatogenesis, during which the spermatids develop into mature spermatozoa. At the beginning of the stage, the spermatid is a more or less circular cell containing a nucleus , Golgi apparatus , centriole and mitochondria ; by the end of the process, it has radically transformed into an elongated ...
The stem cells involved are called spermatogonia and are a specific type of stem cell known as gametogonia. Three functionally separate spermatogonia cell types are recognized on the basis of the appearance of the nuclei : type A dark spermatogonia (Ad), type A pale spermatogonia (Ap), and type B spermatogonia (B).
Spermatogonia going through mitosis to form primary spermatocytes in Grasshopper testes. Spermatocytogenesis. At puberty, spermatogonia located along the walls of the seminiferous tubules within the testis will be initiated and start to divide mitotically, forming two types of A cells that contain an oval shaped nucleus with a nucleolus attached to the nuclear envelope; one is dark (Ad) and ...
Spermatogonial stem cells are the precursors to spermatozoa, which are produced through a series of differentiation steps. [4] This is the alternative SSC outcome to self-renewal. SSCs survive within microenvironments, termed niches, which provide extrinsic stimuli that drive stem cell differentiation or self-renewal. [ 24 ]
Throughout the process of spermatogenesis, there are many different parts of the male anatomy, accessory organs, and hormones. However, spermatogenesis can be broken down in the following steps, which are initiated at the start of puberty: Spermatogenesis occurs in the germinal epithelium of the seminiferous tubules.
Capacitation is the penultimate [1] step in the maturation of mammalian spermatozoa and is required to render them competent to fertilize an oocyte. [2] This step is a biochemical event; the sperm move normally and look mature prior to capacitation.
Because its main function is to nourish developing sperm cells through the stages of spermatogenesis, the Sertoli cell has also been called the "mother" or "nurse" cell. [10] Sertoli cells also act as phagocytes, consuming the residual cytoplasm during spermatogenesis. Translocation of cells from the basal lamina to the lumen of the ...