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Ethyl eicosapentaenoic acid (E-EPA, icosapent ethyl), sold under the brand name Vascepa among others, is a medication used to treat dyslipidemia [4] and hypertriglyceridemia. [3] It is used in combination with changes in diet in adults with hypertriglyceridemia ≥ 150 mg/dL.
Side effects include stomach ache, burping, and a bad taste; some people on very high doses (8g/day) in clinical trials had atrial fibrillation. [3] Omega-3-acid ethyl esters have not been tested in pregnant women and are rated pregnancy category C; it is excreted in breast milk and the effects on infants are not known. [3]
Omega−3-carboxylic acids are used in addition to changes in diet to reduce triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. [6]Intake of large doses (2.0 to 4.0 g/day) of long-chain omega−3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects ...
Amarin's (NAS: AMRN) new triglyceride-lowering drug, Vascepa, could have major advantages for patients over its main competitor -- GlaxoSmithKline's (NYS: GSK) Lovaza -- since one of Lovaza's ...
Vascepa's active ingredients are derived from omega-3 fatty acids found in fish oils, as are the active ingredients. Amarin's (NAS: AMRN) new triglyceride-lowering drug Vascepa may or may not be a ...
Amarin (NAS: AMRN) , the pharma company that recently gained FDA approval for its hypertriglyceridemia drug Vascepa, will post its third-quarter earnings on Nov. 8. Although this therapeutic hasn ...