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Bipolar disorder is a mood disorder characterized by alternating periods of manic (elevated) and depressed mood.While the exact cause and mechanism of bipolar disorder remain unknown, ongoing research focuses on uncovering its biological origins.
The brain-derived neurotrophic factor (BDNF) gene plays a role in the growth, differentiation, and maintenance of neurons.There have been consistent differences observed between bipolar disorder patients and controls in the cytosine methylation levels of the BDNF gene promoter regions 3 and 5.
The diagnosis of bipolar disorder can be complicated by coexisting psychiatric conditions including obsessive–compulsive disorder, substance-use disorder, eating disorders, attention deficit hyperactivity disorder, social phobia, premenstrual syndrome (including premenstrual dysphoric disorder), or panic disorder.
About BD²: Breakthrough Discoveries for thriving with Bipolar Disorder is the first organization focused on funding and advancing research and care for bipolar disorder on a global scale. Our collaborative, open-science approach is designed to transform and shorten the time it takes for scientific breakthroughs to make a meaningful difference ...
Biological psychiatry or biopsychiatry is an approach to psychiatry that aims to understand mental disorder in terms of the biological function of the nervous system.It is interdisciplinary in its approach and draws on sciences such as neuroscience, psychopharmacology, biochemistry, genetics, epigenetics and physiology to investigate the biological bases of behavior and psychopathology.
Bipolar disorder is a long-term mood disorder characterized by major fluctuations in mood — both high and low — that can impact daily functioning and behavior. Bipolar Disorder: 4 Types & What ...