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The diagnosis of bipolar disorder can be complicated by coexisting psychiatric conditions including obsessive–compulsive disorder, substance-use disorder, eating disorders, attention deficit hyperactivity disorder, social phobia, premenstrual syndrome (including premenstrual dysphoric disorder), or panic disorder.
Bipolar disorder is associated with elevated basal and dexamethasone elicited cortisol and adrenocorticotropic hormone (ACTH). These abnormalities are particularly prominent in mania, and are inversely associated with antipsychotic use. [97] The incidence of psychiatric symptoms associated with corticosteroids is between 6% and 32%.
Bipolar disorder is a long-term mood disorder characterized by major fluctuations in mood — both high and low — that can impact daily functioning and behavior. Bipolar Disorder: 4 Types & What ...
Empirical and theoretical work on bipolar disorder has throughout history "seesawed" between psychological and biological ways of understanding. Despite the work of Kraepelin (1921) emphasizing the psychosocial context, conceptions of bipolar disorder as a genetically based illness dominated the 20th century. Since the 1990s, however, there has ...
Bipolar I: People with bipolar I disorder have had at least one manic episode along with a period of major depression or less severe mania. People with bipolar I can also have an episode of ...
Anxiety disorder comorbidity with bipolar disorder is common, as half of people with bipolar disorder are likely to be diagnosed with some form of anxiety disorder. [12] Schizophrenia and bipolar disorder are also considered to be comorbid, [ 13 ] and it has been found that abnormalities in white matter, including the level of myelination and ...