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Caltrate [1] is a brand name calcium supplement sold by Haleon. The brand was originally owned by Pfizer (formerly Wyeth) and GSK and in Japan by Hisamitsu Pharmaceutical. The Caltrate brand is supplied in many different formulas; calcium carbonate (NOT calcium citrate) is the common ingredient serving as the calcium supplement source. [2]
Calcium citrate is recommended for patients with achlorhydria and those on medications that decrease stomach acidity. While calcium carbonate is the most common and least expensive form of calcium and contains 40% of elemental calcium, calcium citrate supplements contain only 21% calcium, requiring more tablets for equivalent dosage.
Here, registered dietitians recommend the best calcium supplements for bone health and offer expert advice on who needs a calcium supplement and why.
[107] [111] [113] [114] [115] Warner-Lambert management was concerned that atorvastatin was a me-too version of rival Merck & Co.'s orphan drug lovastatin (brand name Mevacor). Mevacor, which was first marketed in 1987, was the industry's first statin and Merck's synthetic version – simvastatin – was in the advanced stages of development. [112]
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]
Pitavastatin is indicated for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. [citation needed]A 2009 study of the 104-week LIVES trial found pitavastatin increased HDL cholesterol, especially in patients with HDL lower than 40 mg/dL, who had a 24.6% rise, in addition to reducing LDL cholesterol 31.3%. [5]