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  2. Armodafinil - Wikipedia

    en.wikipedia.org/wiki/Armodafinil

    Armodafinil, sold under the brand name Nuvigil, is a wakefulness-promoting medication which is used to treat excessive daytime sleepiness associated with obstructive sleep apnea, narcolepsy, and shift work disorder. [1] It is also used off-label for certain other indications. [10] The drug is taken by mouth. [1]

  3. List of Schedule III controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_III...

    Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with an equal or greater quantity of an isoquinoline alkaloid of opium [3] [note 1] 9804 Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in ...

  4. Effective dose (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Effective_dose_(pharmacology)

    In pharmacology, an effective dose (ED) or effective concentration (EC) is the dose or concentration of a drug that produces a biological response. [ 1 ] [ 2 ] The term "effective dose" is used when measurements are taken in vivo , while "effective concentration" is used when the measurements are taken in vitro .

  5. Modafinil - Wikipedia

    en.wikipedia.org/wiki/Modafinil

    Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]

  6. Solriamfetol - Wikipedia

    en.wikipedia.org/wiki/Solriamfetol

    Solriamfetol at higher-than-approved doses—specifically doses of 300, 600, and 1,200 mg, which are 2 to 4 times the maximum recommended dose—produces drug-liking responses, including elevated mood and feelings of relaxation, that are similar in degree to those of phentermine (a Schedule IV controlled substance). [1]

  7. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    For many drugs, severe toxicities in humans occur at sublethal doses, which limit their maximum dose. A higher safety-based therapeutic index is preferable instead of a lower one; an individual would have to take a much higher dose of a drug to reach the lethal threshold than the dose taken to induce the therapeutic effect of the drug.

  8. List of modafinil analogues and derivatives - Wikipedia

    en.wikipedia.org/wiki/List_of_modafinil...

    Modafinil is a drug that helps keep people awake and alert (wakefulness-promoting agent or "eugeroic"). [ 1 ] [ 2 ] Most of the listed modafinil analogues are drugs that specifically target dopamine reuptake (reabsorption of a neurotransmitter by a neurotransmitter transporter ) with stronger effects ( selective DRIs with improved potency ...

  9. Threshold dose - Wikipedia

    en.wikipedia.org/wiki/Threshold_dose

    Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]