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Diffuse large B-cell lymphoma (DLBCL) is a cancer of B cells, a type of lymphocyte that is responsible for producing antibodies.It is the most common form of non-Hodgkin lymphoma among adults, [1] with an annual incidence of 7–8 cases per 100,000 people per year in the US and UK.
A study of DLBCL cell lines indicated that 14-3-3ζ proteins may play a role in mediating resistance of DLBCL cells to CHOP. 14-3-3 proteins exert anti-apoptotic activity by interfering with the function of BH3-only proteins and has been validated as a potential molecular target for anticancer therapeutic development in other types of cancers.
Primary central nervous system lymphoma (PCNSL), also termed primary diffuse large B-cell lymphoma of the central nervous system (DLBCL-CNS), [2] is a primary intracranial tumor appearing mostly in patients with severe immunodeficiency (typically patients with AIDS). It is a subtype and one of the most aggressive of the diffuse large B-cell ...
The remaining forms are much less common: [3] DLBCL variants or sub-types of Primary mediastinal B-cell lymphoma; T cell/histiocyte-rich large B-cell lymphoma; Primary cutaneous diffuse large B-cell lymphoma, leg type (Primary cutaneous DLBCL, leg type) EBV positive diffuse large B-cell lymphoma of the elderly
Diffuse large B-cell lymphoma associated with chronic inflammation (DLBCL-CI) is a subtype of the Diffuse large B-cell lymphomas and a rare form of the Epstein–Barr virus-associated lymphoproliferative diseases, i.e. conditions in which lymphocytes infected with the Epstein-Barr virus (EBV) proliferate excessively in one or more tissues.
In 2022 — the most recent year for which mortality data is available — a total of 941,652 people died of heart disease-related condition
Individuals with FA-DLBCL are typically males (~70% of cases) aged 25–96 years (~75% of cases are >50 years old). [6] They present with abnormalities associated with a long-standing (1–20 years [6]): a) cardiac myxoma (i.e. a myxoid tumor of primitive connective tissue in the heart's atrium); b) subdural hematoma (i.e. a collection of blood between the inner layer of the dura mater and the ...
Cubed tofu absorbs the delicious aromatic broth, full of tang and flavor from prepared kimchi, garlic and ginger. A fried egg adds extra protein to this savory soup. View Recipe.