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Understanding the function of genes and their products in the context of cellular and organismal physiology is the goal of process-level annotation. An obstacle of process-level annotation has been the inconsistency of terms used by different model systems. The Gene Ontology Consortium is helping to solve this problem. [27]
A Moran process or Moran model is a simple stochastic process used in biology to describe finite populations. The process is named after Patrick Moran , who first proposed the model in 1958. [ 1 ] It can be used to model variety-increasing processes such as mutation as well as variety-reducing effects such as genetic drift and natural selection .
Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology [b] [1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems.
A model definition in SBML Levels 2 and 3 consists of lists of one or more of the following components: Function definition: A named mathematical function that may be used throughout the rest of a model. Unit definition: A named definition of a new unit of measure, or a redefinition of an existing SBML default unit. Named units can be used in ...
Developmental systems theory, by contrast, assumes that the process/data distinction is at best misleading and at worst completely false, and that while it may be helpful for very specific pragmatic or theoretical reasons to treat a structure now as a process and now as a datum, there is always a risk (to which reductionists routinely succumb ...
The same process model is used repeatedly for the development of many applications and thus, has many instantiations. One possible use of a process model is to prescribe how things must/should/could be done in contrast to the process itself which is really what happens. A process model is roughly an anticipation of what the process will look like.
In developmental biology, pattern formation refers to the generation of complex organizations of cell fates in space and time. The role of genes in pattern formation is an aspect of morphogenesis, the creation of diverse anatomies from similar genes, now being explored in the science of evolutionary developmental biology or evo-devo.
Regulation of biological processes occurs when any process is modulated in its frequency, rate or extent. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.