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Chemotherapy interferes with cell division, which particularly affects rapidly dividing cells like those of the gastrointestinal mucosa and immune cells. Irritation of the GI mucosa by chemotherapy, radiation, distention, or acute infectious gastroenteritis activates the 5-HT 3 receptors of these inputs. [4]
At any stage, children with chronic illness can have reduced quality of life, especially if the children or their families are of low socioeconomic status. [ 31 ] [ 32 ] Malnutrition is a greater risk among children with chronic illnesses, and children's physical and cognitive development may be poorly impacted, such as abnormal immune system ...
Further, it caused 1.8 million deaths in 2020 alone. [3] In those aged 14 or younger, leukaemia is the most frequent form of malignancy with the brain and nervous system subsequent. [26] These individuals account for approximately 1% of the cancer mortality rate – about 110,000 children each year. [28]
Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim only to prolong life or to reduce symptoms (palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called medical oncology. [1] [2]
Their incidences of cardiovascular disease –– including strokes, heart attacks and heart failures–– were collected from the national health registers through 2019, according to the study.
The term childhood disease refers to disease that is contracted or becomes symptomatic before the age of 18 or 21 years old. Many of these diseases can also be contracted by adults. Some childhood diseases include:
Eventually Agler, then 27, learned he had nasopharyngeal rhabdomyosarcoma in his sinuses and mouth, a rare soft tissue cancer that normally occurs in children, according to the National Cancer ...
In children under 15 in first-world countries, the five-year survival rate is greater than 60% or even 90%, depending on the type of leukemia. [13] In children who are cancer-free five years after diagnosis of acute leukemia, the cancer is unlikely to return. [13] In 2015, leukemia was present in 2.3 million people worldwide and caused 353,500 ...