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Infective endocarditis is associated with 18% in-hospital mortality. [24] However, adult patients with congenital heart disease can have relatively lower mortality down to 5% due to younger age, right-sided endocarditis and management by multidisciplinary teams. As many as 50% of people with infective endocarditis may experience embolic ...
The nodes are commonly indicative of subacute bacterial endocarditis. [3] 10–25% of endocarditis patients will have Osler's nodes. [4] Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender. [2]
Nail clubbing, also known as digital clubbing or clubbing, is a deformity of the finger or toe nails associated with a number of diseases, anomalies and defects, some congenital, mostly of the heart and lungs.
Endocarditis is an inflammation of the inner layer of the heart, the endocardium.It usually involves the heart valves.Other structures that may be involved include the interventricular septum, the chordae tendineae, the mural endocardium, or the surfaces of intracardiac devices.
Janeway lesions are rare, non-tender, small erythematous or haemorrhagic macular, papular or nodular lesions on the palms or soles only a few millimeters in diameter that are associated with infective endocarditis and often indistinguishable from Osler's nodes. [1] [2]
The HACEK organisms are a group of fastidious Gram-negative bacteria that are an unusual cause of infective endocarditis, which is an inflammation of the heart due to bacterial infection. [1] HACEK is an abbreviation of the initials of the genera of this group of bacteria: Haemophilus , Aggregatibacter (previously Actinobacillus ...
Roth's spots, also known as Litten spots or the Litten sign, [1] are non-specific red lesions with white or pale centres, seen on the retina of the eye and although traditionally associated with infective endocarditis, can occur in a number of other conditions including hypertension, diabetes, collagen vascular disease, extreme hypoxia, leukemia and HIV.
Splinter hemorrhages (or haemorrhages) are tiny blood clots that tend to run vertically under the nails.Splinter hemorrhages are not specific to any particular condition, and can be associated with subacute infective endocarditis, scleroderma, trichinosis, systemic lupus erythematosus (SLE), rheumatoid arthritis, psoriatic nails, [1] antiphospholipid syndrome, [2]: 659 haematological ...