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Formerly, melatonin was derived from animal pineal tissue, such as bovine. It is now synthetic, which limits the risk of contamination or the means of transmitting infectious material. [64] [69] Melatonin is the most popular over-the-counter sleep remedy in the United States, resulting in sales in excess of US$400 million during 2017. [70]
Norman E. Rosenthal is an American author, psychiatrist and scientist who first described seasonal affective disorder (SAD), and developed light therapy as a treatment. Rosenthal was born and educated in South Africa but moved to the United States to complete his medical training.
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
December is Seasonal Depression Awareness Month, and it's little surprise why. The days are short (the winter solstice on Dec. 21 is the shortest day of the year, in fact), the weather is cold and ...
Melatonin is often touted online as an alternative to. A bad night's sleep can ruin your entire day. Consistently getting poor sleep, though, is enough to make a person crack — or at least turn ...
Sleep deprivation and light therapy both target the same brain neurotransmitter system and brain areas as antidepressant drugs, and are now used clinically to treat depression. [28] Light therapy, sleep deprivation and sleep time displacement (sleep phase advance therapy) are being used in combination quickly to interrupt a deep depression in ...