Ad
related to: cushingoid body habitus- Mechanism of Action
See how this treatment option
works. Learn more.
- Dosing and Monitoring
See optimal dosing and
monitoring guidance.
- Clinical Studies
See efficacy results from two
clinical studies. Review the data.
- Support for HCPs
Get support for your patients and
your practice. Sign up today.
- Mechanism of Action
Search results
Results From The WOW.Com Content Network
Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
Moon face (also known as "Cushingoid facies") – Cushing's syndrome; Elfin facies – Williams syndrome, Donohue syndrome; Potter facies – oligohydramnios; Mask like facies – parkinsonism; Leonine facies – lepromatous leprosy or craniometaphyseal dysplasia [4] Mitral facies – mitral stenosis
[30] [31] Out of the 12 cases with hypercortisolism described in Cushing's monograph on the pituitary body, 67% died within a few years after symptom presentation, whereas Minnie G. survived for more than 40 years after symptom presentation, despite the fact that she did not receive any treatments for a pituitary tumor. [3]
Moon face is often associated with Cushing's syndrome [5] [6] or steroid treatment (especially corticosteroids), which has led to it being known as Cushingoid facies. [ 7 ] Moon face is a type of corticosteroid-induced lipodystrophy along with "buffalo hump", which in one study occurred in 47% of the 820 patients.
Corticosteroid-induced lipodystrophy (CIL) is a condition of abnormal fat deposition caused by corticosteroid medications. [1] Fat accumulates in the facial area ("moon face"), dorsocervical region ("buffalo hump"), and abdominal area ("pot belly" or "beer belly"), whereas the thickness of subcutaneous fat in the limbs is decreased. [1]
However, pseudo-Cushing's syndrome is not caused by a problem with the hypothalamic-pituitary-adrenal axis as Cushing's is; it is mainly an idiopathic condition, however a cushingoid appearance is sometimes linked to excessive alcohol consumption. [1]
Since inline citations are not required for the lead section, and since the detailed explanation of CS etiology (endogenous vs. medication-induced CS) is clearly delineated in the article body, I propose the first paragraph be rewritten as e.g. "Cushing's syndrome is a collection of signs and symptoms caused by prolonged exposure to cortisol or ...
This page was last edited on 25 October 2010, at 14:14 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.