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Acetazolamide is also used for the treatment of acute mountain sickness. In the prevention or treatment of mountain sickness, acetazolamide inhibits the ability of the kidneys to reabsorb bicarbonate, the conjugate base of carbonic acid. Increasing the amount of bicarbonate excreted in the urine leads to acidification of the blood. [12]
Acetazolamide is an inhibitor of carbonic anhydrase.It is used for glaucoma, epilepsy (rarely), idiopathic intracranial hypertension, and altitude sickness. For the reduction of intraocular pressure (IOP), acetazolamide inactivates carbonic anhydrase and interferes with the sodium pump, which decreases aqueous humor formation and thus lowers IOP.
A study by the Denali Medical Research Project concluded: "In established cases of acute mountain sickness, treatment with acetazolamide relieves symptoms, improves arterial oxygenation, and prevents further impairment of pulmonary gas exchange." [38] The folk remedy for altitude sickness in Ecuador, Peru and Bolivia is a tea made from the coca ...
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High-altitude cerebral edema (HACE) is a medical condition in which the brain swells with fluid because of the physiological effects of traveling to a high altitude. It generally appears in patients who have acute mountain sickness and involves disorientation, lethargy, and nausea among other symptoms.
Additional medications that are being considered for prevention but require further research to determine efficacy and treatment guidelines include acetazolamide, salmeterol, tadalafil (and other PDE5 inhibitors), and dexamethasone. [15] [3] [17] Acetazolamide has proven to be clinically effective, but formal studies are lacking. Salmeterol is ...
Whether you're traveling by car, train or boat, motion sickness can feel debilitating. These doctor-approved tips can help you start feeling better. How to get rid of motion sickness, according to ...
Acetazolamide; Altitude sickness; C. Chronic mountain sickness; Climb to Fight Breast Cancer; E. Effects of high altitude on humans; F. Frostbite; H. High-altitude ...