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In the brain, serotonin is a neurotransmitter and regulates arousal, behavior, sleep, and mood, among other things. [9] During prolonged exercise where central nervous system fatigue is present, serotonin levels in the brain are higher than normal physiological conditions; these higher levels can increase perceptions of effort and peripheral muscle fatigue. [9]
The cause of serotonin toxicity or accumulation is an important factor in determining the course of treatment. Serotonin is catabolized by monoamine oxidase A in the presence of oxygen, so if care is taken to prevent an unsafe spike in body temperature or metabolic acidosis, oxygenation will assist in dispatching the excess serotonin. The same ...
Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
However, scientists are unsure what actually causes serotonin deficiency. "Some people are biologically more vulnerable to low serotonin levels and depression," Viswanathan explains. He notes that ...
NHS figures show that the number of people in England taking antidepressants continues to rise, with 8.3m patients receiving them in 2021/22.
If the adult population was 51% female, this would give a female/male split among diagnosed fibromyalgia patients of 80/20. However fibromyalgia may be underdiagnosed in males. A 2018 review said that even though more than 90% of fibromyalgia patients are women, only 60% of people with fibromyalgia symptoms are female in the general population ...
Research shows that older men and women with low testosterone have lower red blood cell counts and an increased risk of developing anemia. Anemia can produce symptoms like fatigue, weakness, loss ...
Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
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