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Although a prospective cohort study of middle-aged women indicated that some flavonoid-rich foods are associated with a reduction in all-cause mortality, frequent grapefruit consumption was associated with a small increase in all-cause mortality, possibly because of the clinically significant drug interactions of the non-flavonoid components. [8]
This is a complete list of estrogens and formulations that are approved by the FDA Tooltip Food and Drug Administration and available in the United States. Estrogens are used as hormonal contraceptives, in hormone replacement therapy, and in the treatment of gynecological disorders.
Estrogens, conjugated is the generic name of the drug and its USP Tooltip United States Pharmacopeia and JAN Tooltip Japanese Accepted Name. [87] It is also known as conjugated estrogens or as conjugated equine estrogens. [10] [unreliable medical source?] The brand name Premarin is a contraction of "pregnant mares' urine". [88] [89] [90]
"Patients must understand that the GLP-1 medications have side effects—they are common and expected, and that particular foods may trigger them," says Dr. Christopher McGowan, MD, a ...
The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...
Most of the drug dose is excreted in the urine but some part is excreted in feces. The largest part of the drug dose is metabolized and less than 10% is excreted unchanged. The liver is the main site of drug metabolism and the drug is metabolized by glucuronidation, hydroxylation and N-dealkylation. The metabolites are mainly excreted in the urine.
Conjugated estrogens/methyltestosterone (CEEs/MT), sold under the brand name Premarin with Methyltestosterone, is a combination of conjugated estrogens (CEEs), an estrogen, and methyltestosterone (MT), an androgen and anabolic steroid (AAR), which is used in menopausal hormone therapy for women.
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds ...