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If you have low levels of dopamine, you might feel tired or unhappy, have low motivation, and could experience mood swings and concentration problems, the Cleveland Clinic says. High levels might ...
Atypical depression also often features significant weight gain or an increased appetite, hypersomnia, a heavy sensation in the limbs, and interpersonal rejection sensitivity that results in significant social or occupational impairment. [4] Despite its name, "atypical" depression does not mean it is uncommon or unusual. [5]
Symptoms must also cause clinically significant distress in important areas of everyday life (e.g. social or occupational). [22] For a diagnosis of a major depressive episode, the patient must also not have a history of manic or hypomanic episodes and their symptoms cannot meet the criteria for a mixed episode .
Some core symptoms of depression, such as rumination, low self-esteem, guilt, and depressed mood cannot be assessed in animals as they require subjective reporting. [130] From an evolutionary standpoint, the behavior correlates of defeats of loss are thought to be an adaptive response to prevent further loss.
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
Instead, dopamine is more closely related to the drive for hunger and thirst. Although the lack of dopamine resulted in adipsia in these rats, low levels of dopamine do not necessarily cause adipsia. [9] The nigrostriatal pathway (highlighted in blue) is crucial for dopamine production and transmission. Location of the hypothalamus in the brain.
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