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The beta-amyloid protein forms insoluble aggregates called amyloid plaques in the space between brain cells. In contrast, the tau protein aggregates to form insoluble fibrils, referred to as ...
Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of amyloid beta (Aβ) ...
Some doctors, including Isaacson, suspect that insulin resistance is one of the causes of Alzheimer’s because it can trigger the development of the disease’s telltale amyloid plaques. “It ...
New preclinical-stage research suggests that targeting a specific protein in the brain could help clear toxic amyloid plaques typically linked to Alzheimer's disease progression.
The prevention of dementia involves reducing the number of risk factors for the development of dementia, and is a global health priority needing a global response. [1] [2] Initiatives include the establishment of the International Research Network on Dementia Prevention (IRNDP) [3] which aims to link researchers in this field globally, and the establishment of the Global Dementia Observatory ...
Aducanumab, sold under the brand name Aduhelm, is an anti-amyloid drug designed to treat Alzheimer's disease. It is a monoclonal antibody that targets aggregated forms (plaque) of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup. [10] It was developed by Biogen and Eisai. [11] Aducanumab is given via intravenous infusion. [5] Aducanumab was ...