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Tamsulosin, sold under the brand names including Flomax and Contiflo, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis and to help with the passage of kidney stones. [6] [7] [8] The evidence for benefit with a kidney stone is better when the stone is larger. [8] Tamsulosin is taken by mouth. [6]
ATC code G04 Urologicals is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Alfuzosin, sold under the brand name Uroxatral among others, is a medication of the α 1 blocker class. It is used to treat benign prostatic hyperplasia (BPH). [1]As an antagonist of the α 1-adrenergic receptor, it works by relaxing the muscles in the prostate and bladder neck, making urination easier.
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Alfuzosin should not be used for patients with renal impairment. [40] [33] Tamsulosin is excreted via urine and 9% of that is unchanged on its active form, elimination half-life for tamsulosin is between 9–13 hours for healthy volunteers. The elimination half-life for target patients is around 14–15 hours.
Alfuzosin [4] Doxazosin [5] Prazosin (inverse agonist) [6] Tamsulosin [7] Terazosin [8] Silodosin [9] Selective α 2-adrenergic receptor antagonists include: Atipamezole; Idazoxan; Mirtazapine; Yohimbine; Finally, the agents carvedilol and labetalol are both α and β-blockers. Below are some of the most common drugs used in the clinic.