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The Common Terminology Criteria for Adverse Events (CTCAE), [1] formerly called the Common Toxicity Criteria (CTC or NCI-CTC), are a set of criteria for the standardized classification of adverse events of drugs and treatment used in cancer therapy. The CTCAE system is a product of the US National Cancer Institute (NCI).
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]
Medications to inhibit the function of p-glycoprotein are undergoing investigation, but due to toxicities and interactions with anti-cancer drugs their development has been difficult. [ 144 ] [ 145 ] Another mechanism of resistance is gene amplification , a process in which multiple copies of a gene are produced by cancer cells.
All medications have the potential to cause side effects. In general, chemoprophylaxis should be initiated only when the benefits of treatment outweigh the risks. The cost associated with chemoprophylaxis may be prohibitive, particularly when the cost of treatment is high or the incidence of the target disease is low.
A woman accessing the PDQ database with an early laptop in 1987. Physician Data Query (PDQ) is the US National Cancer Institute's (NCI) comprehensive cancer database. [1] [2] It contains peer-reviewed summaries on cancer treatment, screening, prevention, genetics, and supportive care, and complementary and alternative medicine; a registry of more than 6,000 open and 17,000 closed cancer ...
Among 28 large cancer centers across the country, 89% reported last month that at least one drug used to either treat cancer, its symptoms or the side effects of treatment was in short supply at ...
A page from Robert James's A Medicinal Dictionary; London, 1743-45 An illustration from Appleton's Medical Dictionary; edited by S. E. Jelliffe (1916). The earliest known glossaries of medical terms were discovered on Egyptian papyrus authored around 1600 B.C. [1] Other precursors to modern medical dictionaries include lists of terms compiled from the Hippocratic Corpus in the first century AD.