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The mechanism of action of bupropion in the treatment of depression and for other indications is unclear. [2] However, it is thought to be related to the fact that bupropion is a norepinephrine–dopamine reuptake inhibitor (NDRI) and negative allosteric modulator of several nicotinic acetylcholine receptors . [ 2 ]
A 10-fold higher dosage of 10 mg/kg is needed to decrease serotonin levels as much as the reduction in dopamine levels at 1 mg/kg. [20] The low-effort bias of systemic administration of tetrabenazine also occurs when it is injected directly into the nucleus accumbens but not the overlying medial neostriatum (i.e., dorsal striatum). [20]
Vistaril (hydroxyzine) – an antihistamine for the treatment of itches and irritations, an antiemetic, as a weak analgesic, an opioid potentiator, and as an anxiolytic Vyvanse ( lisdexamfetamine ) – a pro-drug stimulant used to treat attention deficit hyperactivity disorder and binge eating disorder ; Vyvanse is converted into Dexedrine in vivo
Extended-release tablets of bupropion contain either 150 mg or 300 mg. A typical starting dose of bupropion for depression is 150 mg per day. ... bupropion treatment has no notable effect on anxiety.
Mianserin at higher doses (30–90 mg/day) is used for the treatment of major depressive disorder. [ 6 ] It can also be used at lower doses (around 10 mg/day) to treat insomnia.
Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Abnormal dreams; Aggression; Anaphylactic shock; Angioedema (indicative of a hypersensitivity reaction); Arthralgia; Ataxia; Blood glucose disturbances; Bronchospasm (indicative of a hypersensitivity reaction)
Vic Fangio's coaching career started in the 1970s as a high school assistant in Pennsylvania and has taken him across the country in various stops as he grew into one of the most innovative ...