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A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron.
These are structural analogues and derivatives of modafinil, a drug that affects dopamine levels in the brain in an unusual way (atypical dopamine reuptake inhibitor or DRI). Modafinil is a drug that helps keep people awake and alert ( wakefulness-promoting agent or " eugeroic ").
As of March 2024, the U.S. Environmental Protection Agency finalized regulations banning imports of chrysotile asbestos (effective immediately) due to its link to lung cancer and mesothelioma. However, the new rules can allow up to a dozen years to phase out the use of chrysotile asbestos in some manufacturing facilities. [ 26 ]
CAMBRIDGE, Mass., Oct. 03, 2024 (GLOBE NEWSWIRE) -- Editas Medicine, Inc. (Nasdaq: EDIT), a clinical-stage gene editing company, today announced the sale of certain future license fees and other payments owed to Editas Medicine under its Cas9 license agreement with Vertex Pharmaceuticals to a wholly-owned subsidiary of DRI Healthcare Trust (DRI) for an upfront cash payment of $57 million.
By February 2024, 33 sites across Sydney had tested positive for asbestos, and one in Nowra. [1] As of 7 March, the number of sites within New South Wales had risen to over 75. [7] Dr Jeremy McAnulty from NSW Health stated that asbestos needs to be breathed in to be a risk, and merely touching it is typically not a risk for asbestos-related ...
A new opioid-free pain medication was approved by the U.S. Food and Drug Administration (FDA) on Thursday, marking a non-addictive alternative for patients. Journavx (suzetrigine), made by Vertex ...
Image source: The Motley Fool. Oil-Dri Of America (NYSE: ODC) Q4 2024 Earnings Call Oct 11, 2024, 10:00 a.m. ET. Contents: Prepared Remarks. Questions and Answers. Call Participants
A woman in Indiana is facing charges including reckless homicide after reportedly killing her 25-year-old sister and a 6-year-old girl during a car crash when she was driving at over 100 mph. On ...