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Hypofrontality is a symptom of numerous neurological diseases defined as reduced utilization of glucose and blood flow in the prefrontal cortex. Hypofrontality can be difficult to detect under resting conditions, but under cognitive challenges, it has been seen to correlate with memory deficits along with executive function deficits.
Late-life depression refers to depression occurring in older adults and has diverse presentations, including as a recurrence of early-onset depression, a new diagnosis of late-onset depression, and a mood disorder resulting from a separate medical condition, substance use, or medication regimen. [1]
There are many psychiatric and medical conditions that may mimic some or all of the symptoms of depression or may occur comorbid to it. [11] [12] [13] A disorder either psychiatric or medical that shares symptoms and characteristics of another disorder, and may be the true cause of the presenting symptoms is known as a differential diagnosis. [14]
Individuals with depression often describe a slowing of thought, an inability to concentrate and make decisions, and being easily distracted. [3] In the elderly, the decreased concentration caused by a major depressive episode may present as deficits in memory. [3] This is referred to as pseudodementia and often goes away with treatment. [3]
Central nervous system (CNS) depression is a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death. It is the result of inhibited or suppressed brain activity .
What are the symptoms of transient global amnesia? The classic symptom of TGA is the acute loss of the ability to acquire new memories (anterograde memory loss). There is also often the loss of ...