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Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
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English: Main symptoms of different variants and stages of tuberculosis (See Wikipedia:Tuberculosis), with many symptoms overlapping with other variants, while others are more (but not entirely) specific for certain variants. Multiple variants may be present simultaneously. To discuss image, please see Template talk:Human body diagrams
Ghon's complex is a lesion seen in the lung that is caused by tuberculosis. [1] [2] The lesions consist of a Ghon focus along with pulmonary lymphadenopathy within a nearby pulmonary lymph node. A Ghon's complex retains viable bacteria, making them sources of long-term infection, which may reactivate and trigger secondary tuberculosis later in ...
The two most common commercially available tests are the amplified mycobacterium tuberculosis direct test (MTD, Gen-Probe) and Amplicor. [15] In 2007, review concluded that for diagnosing tuberculous meningitis "Individually, the AMTD test appears to perform the best (sensitivity 74% and specificity 98%)", they found the pooled prevalence of TB ...
Koch first discovered mycobacterium tuberculosis as the cause of tuberculosis in 1892 but the strains he studied were not preserved and it is unclear how related H37Rv may be to those strains. H37Rv has continued to be the strain of tuberculosis most used in laboratories, and was the first to have its complete genome published in 1998. [5]
Mycobacterium tuberculosis (stained red) in tissue (blue).. Acid-fastness is a physical property of certain bacterial and eukaryotic cells, as well as some sub-cellular structures, specifically their resistance to decolorization by acids during laboratory staining procedures.