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Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
Untreated, it can lead to complications and death. [67] Clinical manifestations of syphilis include the ulceration of the uro-genital tract, mouth or rectum; if left untreated the symptoms worsen. In recent years, the prevalence of syphilis has declined in Western Europe, but it has increased in Eastern Europe (former Soviet states).
The study began in 1932, when syphilis was a widespread problem and there was no safe and effective treatment. [27] The study was designed to measure the progression of untreated syphilis. By 1947, the new drug penicillin had been shown to be an effective cure for early syphilis and was becoming widely used to treat the disease. [26]
Cases of syphilis have hit record high numbers following a five-year trend, the Centers for Disease Control and Prevention said. A report published Jan. 30 examined the total cases of three ...
Stage 4: Tertiary Stage - Most people with untreated syphilis do not develop tertiary syphilis, but when it does happen, many different organ systems are affected. These include the heart, blood ...
Syphilis is usually spread from direct contact with a syphilis sore during vaginal, anal or oral sex, according to the CDC, although it can also spread from an infected pregnant women to her ...