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7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). [1] [2] It is a non-selective antagonist of the adenosine receptors. [1] [2] The compound may slow the progression of myopia (nearsightedness). [1] [2] It is under investigation for this ...
Liver metabolism of caffeine Urinary metabolites of caffeine in humans at 48 hours post-dose [1] Methylxanthine is a term applied to any methyl derivative of xanthine, including: With one methyl substituent 1-Methylxanthine; 3-Methylxanthine; 7-Methylxanthine; With two methyl substituents Theophylline (1,3-dimethylxanthine) Paraxanthine (1,7 ...
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To mark the rejuvenation of Moto Guzzi, the first Breva 750 was delivered to its owner on April 7, 2003, in a special ceremony at the Mandello works. Likewise, the first 100 Breva 750's were delivered to their Italian dealers in a special ceremony on March 26, 2003, at Mandello del Lario headquarters on the occasion of the company's anniversary.
1,3,7-Trimethyluric acid is a minor caffeine metabolite. [5] 7-Methylxanthine is also a metabolite of caffeine. [193] [194] Each of the above metabolites is further metabolized and then excreted in the urine. Caffeine can accumulate in individuals with severe liver disease, increasing its half-life. [195]
Interior view, The Moto Guzzi Wind Tunnel, Moto Guzzi Headquarters, Mandello del Lario, Italy, c. 1950s. In 1950 Moto Guzzi created the first motorcycle wind tunnel, [5] La Galleria del Vento, capable of testing 1:1 prototypes at the Mandello del Lario works, thereby allowing the company to market an integral fairing. The wind tunnel enabled ...
In the U.S., Red Dye No. 3 is a synthetic coloring used in candy, medications, and baked goods. You probably know it best from the hue it gives bright-red decorating icing, Valentine's Day sweets ...
The V100 Mandello is the first Moto Guzzi with a liquid-cooled engine and it is the first production motorcycle to introduce a system with adaptive aerodynamics, consisting of a device equipped with aerodynamic wings with electronic adjustment according to the speed placed on the side fairing (the so-called "flaps") which, by opening or closing ...