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Senescence (/ s ɪ ˈ n ɛ s ə n s /) or biological aging is the gradual deterioration of functional characteristics in living organisms. Whole organism senescence involves an increase in death rates or a decrease in fecundity with increasing age, at least in the later part of an organism's life cycle.
Cross-links. Crosslinking of DNA; Free radicals – atom, molecule, or ion that has unpaired valence electrons. With some exceptions, these unpaired electrons make free radicals highly chemically reactive towards other substances, or even towards themselves: their molecules will often spontaneously dimerize or polymerize if they come in contact with each other.
Longevity may refer to especially long-lived members of a population, whereas life expectancy is defined statistically as the average number of years remaining at a given age. For example, a population's life expectancy at birth is the same as the average age at death for all people born in the same year (in the case of cohorts).
But even with the recent dips, U.S. life expectancy has risen considerably over the last century, from 59.6 years for those born in 1922 to 77.5 years for those born in 2022.
Humans may have already reached peak life span, new research suggests. Researchers found that since 1990, the average lifespan has only risen 6.5 years. Experts explain the findings.
As metabolic rate increases, the lifespan of an organism is expected to decrease as a direct result. The rate at which this occurs is not fixed and thus the -45° slope in this graph is just an example and not a constant. The rate of living theory postulates that the faster an organism's metabolism, the shorter its lifespan.
The average life expectancy of someone with this disease is around 46 years. [57] This condition can also affect the weight distribution between the arms, legs, and torso. [ 58 ] Those who have Werner syndrome are at an increased risk for cataracts, type 2 diabetes , different types of cancers, and atherosclerosis . [ 56 ]
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