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Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or (in the United States) Lou Gehrig's disease (LGD), is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction. [3]
The ALS Association is an American nonprofit organization that funds global amyotrophic lateral sclerosis (ALS) research, provides care services and programs to people affected by ALS through its nationwide network of clinical care centers, and works with ALS advocates around the country for state and federal policies that serve people living with amyotrophic lateral sclerosis (ALS), also ...
In the United States and Canada, the term motor neuron disease usually refers to the group of disorders while amyotrophic lateral sclerosis is frequently called Lou Gehrig's disease. [ 2 ] [ 5 ] [ 23 ] In the United Kingdom and Australia, the term motor neuron(e) disease is used for amyotrophic lateral sclerosis, [ 3 ] [ 4 ] although is not ...
Articles relating to amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease. It is a specific disease which causes the death of neurons controlling voluntary muscles. ALS is characterized by stiff muscles, muscle twitching, and gradually worsening weakness due to muscles decreasing in size.
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that typically affects adults around 54–67 [1] years of age, although anyone can be diagnosed with the disease. People diagnosed with ALS live on average 2–4 years after diagnosis due to the quick progression of the disease.
Repetitive transcranial magnetic stimulation had been studied in amyotrophic lateral sclerosis in small and poorly designed clinical trials; as of 2013, there was insufficient evidence to know whether rTMS is safe or effective for ALS. [13]
Examples of neurodegenerative disease include Alzheimer's disease, [14] Parkinson's disease, [15] and amyotrophic lateral sclerosis. [16] For example, multiple sclerosis (MS) is an inflammatory neurodegenerative disease where the body initiate an inflammatory reaction in the central nervous system, and causes damage to neurons.
There are more than 25 genes known to be associated with amyotrophic lateral sclerosis (ALS) as of June 2018, [1] which collectively account for about 70% of cases of familial ALS (fALS) and 10% of cases of sporadic ALS (sALS). [2] About 5–10% of cases of ALS are directly inherited. [3]