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2. Melatonin as a medication and supplement - Wikipedia

   en.wikipedia.org/wiki/Melatonin_as_a_medication...

   Melatonin may be useful in the treatment of delayed sleep phase syndrome. [9] Melatonin is known to reduce jet lag, especially in eastward travel. However, if it is not taken at the correct time, it can instead delay adaptation. [30] Melatonin appears to have limited use against the sleep problems of people who work shift work. [31]

3. Melatonin - Wikipedia

   en.wikipedia.org/wiki/Melatonin

   Melatonin, an indoleamine, is a ... The first patent for the therapeutic use of melatonin as a low-dose sleep aid was ... The plasma maximum concentration of ...

4. Agomelatine - Wikipedia

   en.wikipedia.org/wiki/Agomelatine

   Agomelatine acts as a highly potent and selective melatonin MT 1 and MT 2 receptor agonist (K i = 0.1 nM and 0.12 nM, respectively) and also as a relatively weak serotonin 5-HT 2B and 5-HT 2C receptor antagonist (K i = 660 nM and 631 nM, respectively; ~6,000-fold lower than for the melatonin receptors).

5. Is melatonin or ashwagandha better for sleep? Experts weigh in

   www.aol.com/finance/melatonin-ashwagandha-better...

   For those who wake up in the middle of the night, he recommends a sustained release of a higher dose of melatonin. To reap the sleep benefits of ashwagandha, he says the supplement must be at ...

6. 1 in 5 children under the age of 14 take melatonin ... - AOL

   www.aol.com/1-5-children-under-age-011829011.html

   News of more families turning to melatonin to help restless kids comes after sleep specialists urged parents to consult doctors before melatonin use. 1 in 5 children under the age of 14 take ...

7. Non-24-hour sleep–wake disorder - Wikipedia

   en.wikipedia.org/wiki/Non-24-hour_sleep–wake...

   Then, using endogenous melatonin as a marker for circadian rhythms, several research groups showed that appropriately timed melatonin administration could entrain free-running rhythms in the totally blind: they found that 6 out of 7 patients treated with 10 mg melatonin at bedtime were normally entrained, and when the dose was gradually reduced ...