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  2. Conditions comorbid to autism - Wikipedia

    en.wikipedia.org/wiki/Conditions_comorbid_to_autism

    The prevalence estimates of mitochondrial disease and dysfunction across studies ranging from about 5 to 80%. This may be, in part, due to the unclear distinction between mitochondrial disease and dysfunction. Mitochondrial diseases are difficult to diagnose and have become better known and detected.

  3. Robert K. Naviaux - Wikipedia

    en.wikipedia.org/wiki/Robert_K._Naviaux

    Robert K. Naviaux (born in 1956) is an American physician-scientist who specializes in mitochondrial medicine and complex chronic disorders. He discovered the cause of Alpers syndrome, [1] [2] and was part of the team that reported the first mitochondrial DNA (mtDNA) mutation to cause genetic forms of autism. [3]

  4. Treatment and Education of Autistic and Related Communication ...

    en.wikipedia.org/wiki/Treatment_and_Education_of...

    Strategies used are designed to address the difficulties faced by all people with autism, and be adaptable to whatever style and degree of support is required. [2] TEACCH methodology is rooted in behavior therapy, more recently combining cognitive elements, [ 4 ] guided by theories suggesting that behavior typical of people with autism results ...

  5. Pyruvate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_dehydrogenase...

    Pyruvate dehydrogenase deficiency (also known as pyruvate dehydrogenase complex deficiency or PDCD or PDH deficiency) is a rare neurodegenerative disorder associated with abnormal mitochondrial metabolism. PDCD is a genetic disease resulting from mutations in one of the components of the pyruvate dehydrogenase complex (PDC). [1]

  6. Mitochondrial membrane protein-associated neurodegeneration

    en.wikipedia.org/wiki/Mitochondrial_membrane...

    Mitochondrial membrane protein-associated neurodegeneration (MPAN) is a genetic neurodegenerative disease that causes dystonia, parkinsonism, and iron accumulation in the brain. [ 1 ] [ 2 ] It is caused by mutations to the gene C19orf12 , which has unknown function.

  7. Mechanism of autism - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_autism

    The amygdala, cerebellum, and many other brain regions have been implicated in autism. [15]Unlike some brain disorders which have clear molecular hallmarks that can be observed in every affected individual, such as Alzheimer's disease or Parkinson's disease, autism does not have a unifying mechanism at the molecular, cellular, or systems level.

  8. Mitochondrial disease - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_disease

    Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction. Mitochondria are the organelles that generate energy for the cell and are found in every cell of the human body except red blood cells. They convert the energy of food molecules into the ATP that powers most cell functions.

  9. Mitochondrial neurogastrointestinal encephalopathy syndrome ...

    en.wikipedia.org/wiki/Mitochondrial_neuro...

    Mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE) is a rare autosomal recessive mitochondrial disease. [2] It has been previously referred to as polyneuropathy, ophthalmoplegia, leukoencephalopathy, and intestinal pseudoobstruction (POLIP syndrome). [3] The disease presents in childhood, but often goes unnoticed for decades.