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The dental lamina is a band of epithelial tissue seen in histologic sections of a developing tooth. [1] [2] The dental lamina is first evidence of tooth development and begins (in humans) at the sixth week in utero or three weeks after the rupture of the buccopharyngeal membrane. It is formed when cells of the oral ectoderm proliferate faster ...
The other dominant hypothesis, the "clone model", proposes that the epithelium programs a group of ectomesenchymal cells to generate teeth of particular shapes. This group of cells, called a clone, coaxes the dental lamina into tooth development, causing a tooth bud to form. Growth of the dental lamina continues in an area called the "progress ...
Also during the cap stage is the formation of a depression within the deepest part of each tooth bud of the dental lamina. The dental lamina is a band of epithelial tissue which connects the developing tooth bud to the oral epithelium. The dental lamina eventually disintegrates into small clusters of epithelium and is reabsorbed. The dental ...
The main cells of the lamina propria are the fibroblasts, which are responsible for the production of the fibers as well as the extracellular matrix. The lamina propria, like all forms of connective tissue proper, has two layers: papillary and dense. The papillary layer is the more superficial layer of the lamina propria.
Basement membrane: containing type IV collagen, laminin, fibronectin and integrins. Ideally, the basement membrane must contain a lamina lucida and a lamina densa . Stratified squamous epithelium : is simulated by oral keratinocytes cultured in a medium containing keratinocyte growth factors such as the epidermal growth factor (EGF).
The lamina propria is a thin layer of loose (areolar) connective tissue, which lies beneath the epithelium, and together with the epithelium and basement membrane constitutes the mucosa. As its Latin name indicates, it is a characteristic component of the mucosa, or the mucosa's "own special layer."
Tooth development begins at week 6 in utero, in the oral epithelium. The process is divided into three stages: Initiation; Morphogenesis and; Histogenesis [2]; At the end of week 7 i.u., localised proliferations of cells in the dental laminae form round and oval swellings known as tooth buds, which will eventually develop into mesenchymal cells and surround the enamel organ.
In the inductive stage, the morphodifferentiation phase the shape of the crown is determined by the bell stage of tooth development. There is a basal lamina between the IEE and the dental papilla. [6] At this time, the dentin is not mineralized. The IEE cuboidal or low columnar with centralized nuclei and poorly developed Golgi complexes.