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Ear drops should not be shared to prevent the spread of infection. [7] Ear drops should not be used after the expiration date. [7] Ear drops should only be used in the affected ear. Ear drops are usually used for a short duration of time. Make sure to only use it as prescribed. [7]
Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin. [52] "After multiple-dose administration of 200 mg and 300 mg doses, peak serum levels of 2.2 and 3.6 μg/ml, respectively, are predicted at steady-state.
Acetic acid ear drops may be used as a preventive measure. [3] Treatment of acute cases is typically with antibiotic drops, such as ofloxacin or acetic acid. [2] [3] Steroid drops may be used in addition to antibiotics. [2] Pain medications such as ibuprofen may be used for the pain. [2]
Fluoroquinolones have varying specificity for cytochrome P450, so may have interactions with drugs cleared by those enzymes; the order from most P450-inhibitory to least, is enoxacin > ciprofloxacin > norfloxacin > ofloxacin, levofloxacin, trovafloxacin, gatifloxacin, moxifloxacin. [50]
Otorrhea (ear discharge) is the most common complication of tympanostomy tube placement, affecting between 25–75% of children receiving this procedure. [2] [6] [9] [10] Saline washouts and antibiotic drops at the time of surgery are effective measures to reduce rates of otorrhea, which is why antibiotic ear drops are not routinely prescribed.
Antipyrine and benzocaine ear drops is a medication for the treatment of ear pain caused by otitis media. It combines antipyrine , an NSAID , and benzocaine , a local anaesthetic in order to treat ear pain, alongside hydroxyquinoline sulfate, an antiseptic and preservative.