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Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [1] [4] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. [5]
The approximate calculation for canine efficacy dose is between the range of 1.3 and 1.7 mg/kg, in conjunction with a methylcellulose suspending agent. Based on the calculations from the comparisons of binding affinity of grapiprant to the EP4 receptors of dogs, rats, and humans, the study of plasma and serum protein binding determinations, the ...
Humanoid dog: Wexford County, Michigan: Moa (surviving original populations) [40] [b] Dinornis robustus (South Island giant moa), Dinornis novaezelandiae (North Island giant moa), Anomalopteryx didiformis (Bush moa, little bush moa, or lesser moa) Medium to large flightless birds New Zealand: Mongolian death worm [41] Allghoi (or orghoi) khorkhoi
McNabs are hardy dogs with no breed specific health problems. Their average life span is 13–15 years. McNab dogs may carry the MDR1 mutant gene and can be very sensitive to Ivermectin, which is a common ingredient in heartworm prevention medications. This drug and others can cause serious health problems or even death. [4]
Black silver spotted tabby Mau Black smoke Mau The breed conformation is described as "a balance between the compactness of a Burmese and the slim elegance of a Siamese . Its medium-length body is muscular, with the hind legs longer than the front, giving the Mau the appearance of standing on tiptoes when upright."
Medetomidine is a racemic mixture of two optical or stereoisomers, levomedetomidine and dexmedetomidine. [4] The latter causes the alpha 2- adrenergic agonist effects. [5] It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid that can be administered as an intravenous drug solution with sterile water.
It is the first medication developed specifically for the treatment of cancer in dogs. [4] [5] It is used as its phosphate salt, toceranib phosphate. It was developed by SUGEN as SU11654, [6] a sister compound to sunitinib, which was later approved for human therapies. Toceranib is a tyrosine kinase inhibitor and works in two ways: by killing ...
Maropitant (INN; [3] brand name: Cerenia, used as maropitant citrate , is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [4] [5] and in 2012, for cats. [6]