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Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder.
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
The FDA in 2015 warned that the use of codeine-containing cough medication in children may cause breathing problems. [32] Cold syrup overdose has been linked to visual and auditory hallucinations as well as rapid involuntary jaw, tongue, and eye movements in children. [medical citation needed]
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The recommended adult dose contains: Acetaminophen (650 mg/30 mL) (pain reliever/fever reducer) Dextromethorphan (30 mg/30 mL) (cough suppressant) Doxylamine succinate (12.5 mg/30 mL) (antihistamine/hypnotic) Alcohol (10% by volume) The LiquiCap capsule version has the following active ingredients per pill, half the recommended adult dose:
The sopite syndrome (/ s oʊ ˈ p aɪ t /; from Latin sopire 'to put to sleep') [1] is a neurological disorder that relates symptoms of fatigue, drowsiness, and mood changes to prolonged periods of motion. [2] The sopite syndrome has been attributed to motion-induced drowsiness such as that experienced by a baby when rocked. [1]
Side effects of doxylamine include dizziness, drowsiness, and dry mouth, among others. [4] Doxylamine is a potent anticholinergic and has a side-effect profile common to such drugs, including blurred vision , dry mouth, constipation , muscle incoordination , urinary retention , mental confusion , and delirium .