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  2. Dedifferentiation - Wikipedia

    en.wikipedia.org/wiki/Dedifferentiation

    Metaplasia refers to the change from a fully differentiated cell type to another. This implies that the cell is able to adapt to environmental stimuli, and that it is possible to reverse embryological commitments in the form of differentiation. [20] The idea of metaplasia depends on the ability for a cell to dedifferentiate. [20]

  3. Transdifferentiation - Wikipedia

    en.wikipedia.org/wiki/Transdifferentiation

    It is a type of metaplasia, which includes all cell fate switches, including the interconversion of stem cells. Current uses of transdifferentiation include disease modeling and drug discovery and in the future may include gene therapy and regenerative medicine. [3]

  4. Metaplasia - Wikipedia

    en.wikipedia.org/wiki/Metaplasia

    Micrograph showing apocrine metaplasia of the breast with typical features [3] H&E stain. Barrett's esophagus is an abnormal change in the cells of the lower esophagus, thought to be caused by damage from chronic stomach acid exposure. The following table lists some common tissues susceptible to metaplasia, and the stimuli that can cause the ...

  5. Cellular adaptation - Wikipedia

    en.wikipedia.org/wiki/Cellular_adaptation

    Metaplasia occurs when a cell of a certain type is replaced by another cell type, which may be less differentiated. It is a reversible process thought to be caused by stem cell reprogramming. Stem cells are found in epithelia and embryonic mesenchyme of connective tissue. A prominent example of metaplasia involves the changes associated with ...

  6. Reverse transfection - Wikipedia

    en.wikipedia.org/wiki/Reverse_transfection

    Reverse transfection is a technique for the transfer of genetic material into cells.As DNA is printed on a glass slide for the transfection process (the deliberate introduction of nucleic acids into cells) to occur before the addition of adherent cells, the order of addition of DNA and adherent cells is reverse that of conventional transfection. [1]

  7. Intestinal metaplasia - Wikipedia

    en.wikipedia.org/wiki/Intestinal_metaplasia

    Intestinal metaplasia is the transformation of epithelium (usually of the stomach or the esophagus) into a type of epithelium resembling that found in the intestine. In the esophagus, this is called Barrett's esophagus .

  8. Metaplastic carcinoma - Wikipedia

    en.wikipedia.org/wiki/Metaplastic_carcinoma

    Metaplastic carcinoma, otherwise known as metaplastic breast cancer (MBC), is a heterogeneous group of cancers that exhibit varied patterns of metaplasia and differentiation along multiple cell lines.

  9. Dysplasia - Wikipedia

    en.wikipedia.org/wiki/Dysplasia

    In one of the modern histopathological senses of the term, dysplasia is sometimes differentiated from other categories of tissue change including hyperplasia, metaplasia, and neoplasia, and dysplasias are thus generally not cancerous. An exception is that the myelodysplasias include a range of benign, precancerous, and cancerous forms. Various ...