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  2. Complement component 3 - Wikipedia

    en.wikipedia.org/wiki/Complement_component_3

    Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the complement system of vertebrate animals and contributes to innate immunity. In humans it is encoded on chromosome 19 by a gene called C3. [5] [6]

  3. C3-convertase - Wikipedia

    en.wikipedia.org/wiki/C3-convertase

    C3 convertase (C4bC2b, formerly C4b2a) belongs to family of serine proteases and is necessary in innate immunity as a part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and cell lysis.

  4. Acquired C1 esterase inhibitor deficiency - Wikipedia

    en.wikipedia.org/wiki/Acquired_C1_esterase...

    Diagnosis usually consists of medical evaluation in addition to laboratory testing. Laboratory evaluation includes complement studies, in which typical cases demonstrate low C4 levels, low C1q levels, and normal C3 levels. [3] Determining the etiology, or cause, of acquired angioedema is often helpful in providing appropriate management of AAE.

  5. Complement component 4 - Wikipedia

    en.wikipedia.org/wiki/Complement_component_4

    The cleavage of the C4 results in C4b bearing a thioester functional group [-S-C(O)-]: work in the 1980s on C3, and then on C4, indicated the presence, within the parent C3 and C4 structures, of a unique protein modification, a 15-atom (15-membered) thionolactone ring serving to connect the thiol side chain of the amino acid cysteine (Cys) in a ...

  6. St. Christopher's Hospital for Children - Wikipedia

    en.wikipedia.org/wiki/St._Christopher's_Hospital...

    St. Christopher's Hospital for Children offers health care services for children from birth through 21 years of age. [12] Pediatric services include sub-specialties such as cardiology, endocrinology, gastroenterology, nephrology, neurology, pulmonology, oncology, and rheumatology. [13]

  7. Children's Hospital Oakland Research Institute - Wikipedia

    en.wikipedia.org/wiki/Children's_Hospital_Oakland...

    Children's Hospital Oakland Research Institute (CHORI) is a biomedical research institute affiliated with California’s pediatric medical center, UCSF Benioff Children's Hospital Oakland. [ 1 ] CHORI is based in Oakland, California , and operates a 100,000-square-foot (9,300 m 2 ) biomedical research facility [ 2 ] that houses 300 staff members.

  8. Complement fixation test - Wikipedia

    en.wikipedia.org/wiki/Complement_fixation_test

    The complement fixation test is an immunological medical test that can be used to detect the presence of either specific antibody or specific antigen in a patient's serum, based on whether complement fixation occurs. It was widely used to diagnose infections, particularly with microbes that are not easily detected by culture methods, and in ...

  9. List of medical tests - Wikipedia

    en.wikipedia.org/wiki/List_of_medical_tests

    The tests are classified by speciality field, conveying in which ward of a hospital or by which specialist doctor these tests are usually performed. The ICD-10-CM is generally the most widely used standard by insurance companies and hospitals who have to communicate with one another, for giving a overview of medical tests and procedures.