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  2. Fatal insomnia - Wikipedia

    en.wikipedia.org/wiki/Fatal_insomnia

    Fatal insomnia is an extremely rare neurodegenerative prion disease that results in trouble sleeping as its hallmark symptom. [2] The majority of cases are familial (fatal familial insomnia [FFI]), stemming from a mutation in the PRNP gene, with the remainder of cases occurring sporadically (sporadic fatal insomnia [sFI]).

  3. These siblings have a disease that will one day stop them ...

    www.aol.com/news/2016-05-05-these-siblings-have...

    The stages of the disease include progressively worsening insomnia, which leads to hallucinations, delirium, confusional states like that of dementia and, ultimately, death.

  4. Sleep disorder - Wikipedia

    en.wikipedia.org/wiki/Sleep_disorder

    The most common sleep-related symptom of bipolar disorder is insomnia, in addition to hypersomnia, nightmares, poor sleep quality, OSA, extreme daytime sleepiness, etc. [27] Moreover, animal models have shown that sleep debt can induce episodes of bipolar mania in laboratory mice, but these models are still limited in their potential to explain ...

  5. Hypermetabolism - Wikipedia

    en.wikipedia.org/wiki/Hypermetabolism

    Fatal familial insomnia: Manifestation: Hypermetabolism in the thalamus occurs and disrupts sleep spindle formation that occurs there. [4] Graves' disease: Manifestation: Excess hypermetabolically-induced thyroid hormone activates sympathetic pathways, causing the eyelids to retract and remain constantly elevated. [5]

  6. Insomnia: causes, symptoms, treatments and how it affects you

    www.aol.com/lifestyle/insomnia-causes-symptoms...

    Chronic insomnia often requires more comprehensive treatment to help you address underlying causes, implement healthy sleep habits and learn techniques to manage sleep-disrupting thoughts and ...

  7. Excessive daytime sleepiness - Wikipedia

    en.wikipedia.org/wiki/Excessive_daytime_sleepiness

    The test is based on the idea that the sleepier people are, the faster they will fall asleep. [15] [16] The Maintenance of Wakefulness Test (MWT) is also used to quantitatively assess daytime sleepiness. This test is performed in a sleep diagnostic center. The test is similar to the MSLT as it also relies on a measurement of initial sleep latency.