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Within the epidermis keratinocytes are associated with other cell types such as melanocytes and Langerhans cells. Keratinocytes form tight junctions with the nerves of the skin and hold the Langerhans cells and intra-dermal lymphocytes in position within the epidermis.
Non-keratinized surfaces must be kept moist by bodily secretions to prevent them from drying out. Cells of stratum corneum are sometimes without keratin and living. Examples of non-keratinized stratified squamous epithelium include some parts of the lining of oral cavity , pharynx , conjunctiva of eye , upper one-third esophagus , rectum ...
Eventually the nucleus and cytoplasmic organelles disappear, metabolism ceases and cells undergo a programmed death as they become fully keratinized. In many other cell types, such as cells of the dermis, keratin filaments and other intermediate filaments function as part of the cytoskeleton to mechanically stabilize the cell against physical ...
Simple columnar, non-ciliated: intestinal epithelium: digestive: large intestine: Simple columnar, non-ciliated: intestinal epithelium: digestive: rectum: Simple columnar, non-ciliated - digestive: anus: Stratified squamous, non-keratinized superior to Hilton's white line Stratified squamous, keratinized inferior to Hilton's white line ...
Non-keratinized squamous epithelia, except cornea [6] Cytokeratin 14: Basal layer of stratified and combined epithelia [6] Cytokeratin 18: Glandular epithelia of the digestive, respiratory, and urogenital tracts, both endocrine and exocrine cells, as well as mesothelial cells; Adenocarcinomas originating from those above [6] Cytokeratin 19
By layer, epithelium is classed as either simple epithelium, only one cell thick (unilayered), or stratified epithelium having two or more cells in thickness, or multi-layered – as stratified squamous epithelium, stratified cuboidal epithelium, and stratified columnar epithelium, [8]: 94, 97 and both types of layering can be made up of any of ...
This complex surrounds cells in the stratum corneum and contributes to the skin's barrier function. Corneodesmosomes (modified desmosomes) facilitate cellular adhesion by linking adjacent cells within this epidermal layer. These complexes are degraded by proteases, eventually permitting cells to be shed at the surface. Desquamation and ...
Non-keratinized squamous epithelium covers the soft palate, lips, cheeks and the floor of the mouth. Keratinized squamous epithelium is present in the gingiva and hard palate . [ 3 ] Keratinization is the differentiation of keratinocytes in the granular layer into dead surface cells to form the stratum corneum.