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Pioglitazone, sold under the brand name Actos among others, is an anti-diabetic medication used to treat type 2 diabetes. [3] It may be used with metformin , a sulfonylurea , or insulin . [ 3 ] [ 4 ] Use is recommended together with exercise and diet. [ 4 ]
Pioglitazone/metformin is contraindicated in people with known hypersensitivity to any components of this combination. These combination also contraindicated in renal disease which may also result from conditions, e.g., acute myocardial infarction , sepsis , acute or chronic metabolic acidosis , including diabetic ketoacidosis , with or without ...
Pioglitazone makes cells (fat, muscle and liver) more sensitive to insulin, which means that the body makes better use of the insulin it produces. [1] Glimepiride is a sulphonylurea: it stimulates the pancreas to produce more insulin. [ 1 ]
Pioglitazone (Actos), France and Germany have suspended its sale after a study suggested the drug could raise the risk of bladder cancer. [8] Rosiglitazone (Avandia), which was put under selling restrictions in the US and withdrawn from the market in Europe due to some studies suggesting an increased risk of cardiovascular events. Upon re ...
Thiazolidinediones (Tzd) – pioglitazone, Actos generic; Alpha-glucosidase inhibitors – Acarbose; Meglitinides – nateglinide; Combination of sulfonylureas plus metformin – known by generic names of the two drugs; No generics are available for dipeptidyl peptidase-4 inhibitors (Onglyza), the glifozins, the incretins and various combinations.
A single dose of raw cinnamon before a meal containing complex carbohydrates decreases the postprandial hyperglycemia (higher than 140 mg/dL; >7.8 mmol/L) in patients with type II diabetes. [1] Another plant attracting a lot of attention is Salacia oblonga. [15]
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