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Cardiomyopathies are either confined to the heart or are part of a generalized systemic disorder, both often leading to cardiovascular death or progressive heart failure-related disability. Other diseases that cause heart muscle dysfunction are excluded, such as coronary artery disease, hypertension, or abnormalities of the heart valves. [17]
Model of a normal heart (left); and a weakened heart, with over-stretched muscle and dilation of left ventricle (right); both during diastole. Heart failure is caused by any condition that reduces the efficiency of the heart muscle, through damage or overloading.
Stone heart syndrome (also known as ischemic myocardial contracture) is a rare and severe condition characterized by extreme rigidity and hardness of the heart muscle. This condition typically occurs during high-risk situations such as heart surgery or following a severe heart attack , often leading to life-threatening complications.
The main pathophysiology of heart failure is a reduction in the efficiency of the heart muscle, through damage or overloading. As such, it can be caused by a wide number of conditions, including myocardial infarction (in which the heart muscle is starved of oxygen and dies), hypertension (which increases the force of contraction needed to pump blood) and cardiac amyloidosis (in which misfolded ...
Angina is typically the result of partial obstruction or spasm of the arteries that supply blood to the heart muscle. [3] The main mechanism of coronary artery obstruction is atherosclerosis as part of coronary artery disease. Other causes of angina include abnormal heart rhythms, heart failure and, less commonly, anemia. [4]
A condition called peripheral artery disease (PAD), for example, occurs when the arteries that carry blood from the heart to the legs get clogged; it’s associated with an increased risk of heart ...
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