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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
Common over-the-counter medicines that can cause headaches when overused include Excedrin Migraine, Cafergot, and Advil. [11] [12] Dietary and medicinal caffeine consumption appears to be a modest risk factor for chronic daily headache onset, regardless of headache type. [13] [14] A lifelong history of headaches is a major risk factor for MOH. [15]
While these over-the-counter meds don’t treat nausea, a common symptom of motion sickness, Qing says these are effective when it comes to treating a headache that motion sickness often brings on.
The cause of serotonin toxicity or accumulation is an important factor in determining the course of treatment. Serotonin is catabolized by monoamine oxidase A in the presence of oxygen , so if care is taken to prevent an unsafe spike in body temperature or metabolic acidosis, oxygenation will assist in dispatching the excess serotonin.
Headaches are a common side effect of ED medications such as sildenafil (the active ingredient in Viagra), tadalafil (Cialis) and vardenafil (Levitra), with about 25 percent of men prescribed ...
Researchers studied over 100 volunteers between the ages of 25 and 75 who donated blood or provided biological samples every few months over nearly two years, assessing changes in over 135,000 ...
Treatment options to prevent PONV include medications such as antiemetics (for example, ondansetron or dexamethasone) or other drugs including tropisetron, dolasetron, cyclizine, and granisetron. Droperidol may cause QT prolongation and is not frequently used. [1]
Ondansetron is a racemate but the stereochemistry of the asymmetric carbon atom is not an important factor in the 5-HT 3 receptor interaction. Annelation of the 1,7-positions of the indole nucleus of ondansetron results in increased affinity for the receptor. [49]