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Urethral syndrome is defined as symptoms suggestive of a lower urinary tract infection but in the absence of significant bacteriuria with a conventional pathogen. [1] It is a diagnosis of exclusion in patients with dysuria and frequency without demonstrable infection. [2] In women, vaginitis should also be ruled out. [3]
The symptoms of urethritis can include pain or a burning sensation upon urination , a white/cloudy discharge and a feeling that one needs to pass urine frequently. For men, the signs and symptoms are discharge from the penis, burning or pain when urinating, itching, irritation, or tenderness.
In women, urethritis can be diagnosed with a number of tests including: urine test, blood test, vaginal culture, cytoscopy, or a nucleic acid test. [18] Women will also have abdominal and pelvic exams to check for urethral discharge, and tenderness of the lower abdomen or urethra. [6]
Estimates of the percentage of female adolescents and women of reproductive age affected are between 50% and 90%. [4] [6] It is the most common menstrual disorder. [2] Typically, it starts within a year of the first menstrual period. [1] When there is no underlying cause, often the pain improves with age or following having a child. [2]
Large studies of patients have also failed to show any correlation between lower urinary tract symptoms and a specific diagnosis. [11] Also, recently a report of lower urinary tract symptoms even with malignant features in the prostate failed to be associated with prostate cancer after further laboratory investigation of the biopsy. [10]
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One of the most common causes of dysuria is urinary tract infection. Urinary tract infections are more common in females than in males due to anatomical differences between them. Females have a comparatively shorter and straight urethra, whereas males have a longer and curved urethra.
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